The Right Phenibut Dosage For Destroying Depression And Avoiding Withdrawal

Phenibut or β-Phenyl-γ-aminobutyric acid, is an over the counter anti-anxiety medication which is sold as a nutritional supplement in North America, and a prescription drug in Russia. Phenibut was originally discovered in the former Soviet Union in the 60’s, and has been used in Russia to treat anxiety, insomnia and PTSD.

Phenibut is included in the Russian astronauts medical kit because it’s one of the only tranquilizers that lowers stress levels without negatively affecting performance. It’s a phenyl derivative of the inhibitory neurotransmitter GABA acting as a GABA agonist by binding to the GABAb receptor. The GABAb receptor is responsible for the regulation of anxiety and stress, GHB, alcohol and the prescription drug Baclofen also work as GABA agonists.

Phenibut in moderation is the best drug I’ve ever taken. Once the drug kicked in I immediately realized how powerful it was, within 4 hours of taking Phenibut I became happy, music sounded amazing and I was still completely functional, it was like a chemical version of rose-coloured glasses. I fell in love immediately.

Since then I’ve been experimenting with various doses and methods of taking it and have found what I think is the best dosing schedule.I initially started using Phenibut once per week with great results. I increased the dosage and noticed my sales figures rising on the days I took the drug. I then upped the dosage to 5 days per week at about a gram to 2 grams per day and watched my sales figures triple. Not only that but selling became fun for the first time in my career.

I had read horror stories online about tolerance building so I made sure to keep it to once per week, at least at first, I’m disciplined and never had a problem with this, but I’m always looking to experiment and wanted to see what would happen if I upped the dosage, plus the extra money was just too tempting to give up.

I ended up using it 5 days per week as a sales performance aid for about 5 months, never breaking my discipline despite having to go through a moderate withdrawal on the weekend. Eventually the weekend withdrawal became too brutal for me, despite the extra money I quit the drug and I went through a strong physiological withdrawal for about a week that was pretty nasty. I definitely don’t recommend 5 days a week on for anybody.

I let the Phenibut clear out of my system for a month and slowly started ramping up the dose to 3 times per week at 1, 1.5 and 2 grams, which is the ideal Phenibut dosage for me with tolerance seeming to have plateaued. If you’re going to experiment with Phenibut make sure you follow the dosage guidelines.

Phenibut can be addictive for some people and the withdrawal from continuous use is nasty, many guys have compared it to coming off benzos. With that in mind, used in moderation once or twice a week I’ve noticed almost no side effects and no hangover the next day. Here’s everything you need to know:

The Right Phenibut Dosage For Depression And Avoiding Withdrawal

  • Phenibut is sold legally over the counter in North America, and as a prescription drug in Russia
  • I recommend phenibut from Liftmode, it’s top quality at the best pricess
  • Phenibut should be taken in the morning on an empty stomach with a stimulant, I use between 100 to 200 mgs of caffeine with no food for at least 4 hours afterwards
  • The fast and stimulant combination potentiate the energy enhancing effects and help prevent drowsiness or spaciness
  • A good beginners dose is 1 gram, if you don’t feel much after 2 hours take another 500 mgs
  • A veterans dose will be between 1.5 to 2 grams
  • I take phenibut 3 times a week, in doses of 1 gram, 1.5 grams and 2 grams I find this the ideal regimen for me and haven’t noticed any tolerance
  • 3 times should be your maximum for the week, if you wanted to stay on the safer side keep it to 1 or 2 days per week
  • $38.88/200 grams (less with the discount)
  • 2 hours on an empty stomach, 4 hours on a full stomach
Half Life
  • 5 hours, but effects can be felt lingering for 24 hours
Positive Effects
  • A subtle but powerful relaxation as well as a mood lift that lasts well into the next morning giving you a Phenibut afterglow instead of a hangover
  • Phenibut makes sex amazing especially long sessions where you hold off on ejaculation
  • On Phenibut I find its easy to access that childhood state of happiness, this is a state I almost never reach without the drug, its a feeling of happiness combined with excitement and a love for the world
  • My anxiety cues in my stomach don’t activate, I try and be mindful where in my body certain feelings activate, anxiety always begins in the stomach and I feel phenibut neutralizes them
  • Music becomes really enjoyable
  • Energy is increased
  • Inhibitions are lowered similar to alcohol making socializing easy and fun
  • Sales performance is enhanced
  • Sleep comes easily
Side Effects
  • Slight cognitive spaciness, I find I’m more easily distracted and my short term memory is worse
  • Because Phenibut is anti-inhibitory I find it harder to control anger and sadness as well as being more prone to impulsive behavior ie. buying junk food at the grocery store
  • Lowers your tolerance to alcohol
  • Tolerance builds quickly
  • 9/10
  • I would absolutely recommend Phenibut in moderation to anyone looking for a mood lift, an increase in energy, and a decrease in anxiety, Phenibut is the best drug I’ve ever taken
  • I would also recommend Phenibut as a performance enhancer for sales presentations, parties, interviews, client meetings or obligations (funerals, plays, boring family dinner parties), just don’t mix Phenibut with alcohol or at the most 3 beers
  • I wouldn’t recommend Phenibut to any one with prior substance abuse problems, especially alcohol, this is a powerful drug and tolerance and physiological dependence develops quickly
  • Take 1 to 3 times per week at doses of 1 to 2 grams, take fasted in the morning with 100 mg to 200 mg of caffeine

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  1. Hey RVD,

    Love the article. I’ve actually been looking for something as a substitute for alcohol, and your blog just happens to be one of the ones i frequent. It’s such a coincidence that i happen to find exactly what i’m looking for. If i wanted to use this as a substitute for alcohol for parties at night time, would you still recommend taking it in the morning anyway or just taking it closer to the time of the party? Also in your experience is Phenibut the best alcohol substitute? Thanks for the help in advance.

    Great article, keep them coming!

  2. Hey Izzy, great to hear thanks for the support!

    For me Phenibut carries into the night although not as strong in the afternoon. What I would do is take it alone in the morning as per the dosing protocol in the article and see how it affects you, then what you can do if you like the effect is before the party top up with maybe 500 mg. In my opinion its a great substitute for alcohol, just be careful about mixing the two at a party because Phenibut strengthens the effects of alcohol.

  3. Hey RLD are there any pharmacies/health stores in Toronto that sell this stuff or can you only get it through those internet sources you’ve posted?

  4. Hey A.J., not as far as I know. I just ordered the Liftmode Free Amino Acid Phenibut which is top quality so you can add that to the list, it ships quickly and cheaply.

  5. Okay well the powdered forms, how do you measure out dosages, Do they give you a little 1g scooper or what?

  6. Liftmode gives you a 6.25cc scoop that will hold 250 mgs. Powder City/Health Supplement Wholesalers gives you a scoop as well but the weight is approximate. Happy Hippo doesn’t give a scoop as per my last order. I use a ten dollar digital scale for measuring everything I take to make sure I get the exact dosage I want.

  7. I’ve been doing 1.4 grams 5 days a week with 2 days off (obviously) and the 2 days off do really suck. I’ve been doing this for a couple of years. Now, I still find the 5 days worth it for the 2 crappy days. And really the first day is not that bad, it’s the second day that sucks. I’ve tried numerous supplements to counter the withdrawl and nothing helps that much except small amounts of Xanax which I have never abused. I have never increased my dose of Phenibut. By the end of the 5 days, the effects show some signs of wearing off, but are still noticable. Here’s my question. Do you think that reducing quantity a couple days a week (like if I dropped to 500mg twice out of the 5 days) would make much difference or if I took one extra day off, or do you think that any break should have a minimum 2 day washout. My schedule is M-Saturday 400,600,400 then Sun and Mon off.

  8. Thats the same experience as my five day experiment, the second day off was brutal. In my opinion you should try and get it down to 3 days a week, then you can do 4 days burning kratom if you have to. I do three days a week with no withdrawal symptoms at all, in fact the next day I get a nice phenibut hangover. Definitely don’t do more than five days a week. As far as doing 1.4 grams for 3 days and 500 mg on the other two days, that might cut the weekend withdrawal but I don’t know for sure. Would be worth a test though, and if anything it has you doing less phenibut.

  9. Thanks for the response… I’m backing down first to 1 gram/day for 5 days, that will lower me to 5 grams vs. 7 grams per week. Are your phenibut days consecutive? I’m going to experiment some more. Today after a really crappy withdrawal day I decided to take 200mg instead of my 400mg and the anxiety did go away…much more noticably after 2nd 200mg dose, so I probably could take a lower dose without noticing it that much. But I will try a short taper and see if that helps…

  10. Anytime, I think lowering the dosage is a good plan as opposed to cold turkey. My days are Wednesday, Friday, Sunday. Let me know how the taper goes and lowered dosage.

  11. Underrated article, this is truly a gem. I’ve weaned myself off of a 5 gram dose / day with this. It feels so much better doing it in lower doses – far more healthy, cost-saving, and you avoid that yucky urine taste.

  12. Hey Will – Love your writing! I’m 45, in decent shape, and happy. But the past couple years I’ve had reduced sex drive and erectile dysfunction. Looking at Phenibut and Yohimbine HCL and Tadacip (Cialis). What do you receommend I first try (and in what order, what dosage, and what schedule?) Also would love best places to buy.

  13. Thanks Randal. Cialis for sure, that will probably be all you need. Also at 45, you might want to check with your doctor about yohimbine, it can affect your blood pressure. Next up you should get your testosterone levels checked, I’d be willing to bet they fall at the low end of the range. Once a man hits 30 they tend to lose about 2% of their peak testosterone a year, you very well could be at 30% less or more than you’re 18 year old self. Every man over 40 in my opinion should consider hormone replacement therapy.

    Also make sure to get your heart checked, erectile dysfunction can be a leading indicator of heart disease. The other option would be venous leakage, meaning a problem with blood vessels in the penis, at this point in time doctors won’t advocate surgery as it can be ineffective but at least you’ll know the cause, if you have venous leakage they’ll just give you cialis for it.

  14. I totally appreciate your honesty here, it’s refreshing. Are you still actively using this supplement?

  15. Hey great post. Just curious have you found there to be any withdrawl or tolerance by doing it three times a week? I do it once now with great results and am really tempted to bump it up to two or three – but there are a lot of horror stories out there and warnings not to do it that often

  16. Hey James, I’ve found a slight increase in tolerance but not much in the way of withdrawal. If you’re worried I would bump it up to two times a week first and see how you feel at that dosage.

  17. Hey Will, how many days after taking phenibut should I wait if I want to get intoxicated on alcohol? Could I take a regular dose of phenibut on a Thursday morning and get hammered on that Friday night without it amplifying the affects of the alcohol?

  18. Hey man, cool article. Unfortunately I have depression, ADD and substance misuse issues. When I discovered Phenibut about 2 years ago the combination with dextroamphetamine was such a powerful antidepressive anxiolytic that I abused it, thinking I’d deal with any problems ‘later’. I only became partially tolerant so I continued to take 5-8mg a day with no apparent problems. Well ‘later’ has arrived. That dose is ineffective and higher doses has adverse side effects, like IBS. What do you suggest is the best I take myself off it?

  19. Hey Time Out, yes I definitely think you should take yourself off it. This goes for any guy who has substance abuse problems as I outlined in the article. Abusing phenibut at large daily doses is no joke, you can read the horror stories online. Unfortunately the guys who need the drugs the most are at the highest risk for abuse. You could theoretically use Kratom to help wean yourself off the phenibut and rotate strains daily but I worry that you would end up abusing that as well so I don’t feel comfortable recommending that to you. What you might want to do is try therapy, cognitive behavioral therapy or CBT seems to be the most effective method. I haven’t tried it but its the only method of therapy with science and consistency behind it, might be worth a shot. Also have a look at my fighting depression article for all the things you can do naturally – no ejaculation, getting up early, using caffeine and intermittent fasting and exercising every day have massive positive benefits.

  20. Great website. Just ordered from HH and will try out. They also sent me some Kratom… any suggestion as to how/when to take that? It’s the pleasant green hippo.
    Have spent a good 4 hours throughout your site and just two things I’ll suggest:
    – Get a better microphone to record your audio segments. Sounds like you’re in a cave and sometimes it’s really hard to understand you. A headset mic or something with noise/echo cancellation should do wonders (google podcast microphone… $40 well spent)
    – Be conscious of how many “umms” you say :) most of us are guilty of this, but until someone points it out, you won’t kick the habit. Try listening to one of your podcasts and tally up the # of “umms”

    Keep up the good work. Will start with one dose per week tomorrow and see if I notice any changes. Will try to update again in a month

  21. Thanks Leo, just check out the kratom guide in lifestyle for how to take that.

    Thanks for your suggestions. I’m actually going through and redoing a lot of the audios right now, with my podcast mic, most of the older ones were converted videos from youtube videos so the quality isn’t great, they should be up within the next week.

  22. This is the best, most accurate review of phenibut that I’ve come across. One thing that’s interesting is that, for me, I had to take phenibut a few times (over the course of a week) before I started getting best benefit from it. — The first couple of times I was like, ‘Blah, so it feels like a weak benzo….so what?!’ But now that I’m getting accustomed to it, there’s a huge lift to my attitude & outlook on life. I wake up feeling positive, all of a sudden. And this can be 12-18 hrs. after my last dose. Interesting stuff indeed.

  23. Thanks man. Ya there is a long learning curve on getting your phenibut IQ right, the keys for me are morning dose, plus fasting, plus caffiene. As for waking up the next day I get the same, a nice “hangover” glow.

  24. “Because Phenibut is anti-inhibitory I find it harder to control anger and sadness as well as being more prone to impulsive behavior.”

    OH YES, how I’ve noticed. This has actually caused problems in my life. I mean, when on phenibut, if I think somebody had ‘slighted me’ I REALLY feel hurt. And then I REALLY get angry. And then I say something which gets me into trouble.

    When not on phenibut, I don’t get these extreme feelings. So your observation is right on the money. And I wish persons would consider this ‘side effect’ before beginning the phenibut journey.

  25. Yep, it can definitely have that effect, the same as guys who get angry or emotional when they’re drunk. For anyone who finds it to be too much I recommend dropping the phenibut.

  26. Hey, when looking online for Phenibut, I seem to find a few different kinds. HCL, a crystal, and FAA (free amino acid) do you know which one? the hipp site is double the price of other websites.

  27. Hey, I was wondering if you get hit with any duty fees from either HH or Liftmode? Liftmode has a few shipping options, some that offer duty prepaid and I’m wondering if I should take the chance and just use the regular shipping. Thanks!

  28. I can’t say for sure brother, because I don’t know the rules for your country, with that said I’d probably roll the dice for the first time and if you get dinged you know the right move for the reorder.

  29. I wish this mixed with alcohol but trust me IT DOESNT. I woke up not knowing how I got home. Be careful with this stuff guys.

  30. Yeah, overdoing it with phenibut — even when you don’t mean to overdo it — causes some pretty scary amnesia. Like blackouts, One time I was walking in my own neighborhood and suddenly I didn’t recognize anything, I felt lost. I couldn’t figure whether to make a left or a right at the intersection to get home, and I knew the neighborhood very well. That scared me. Other times I’d wake up after a deep phenibut sleep and had absolutely no clue what day it was. I furiously put on my clothes, thinking I was late for work, only to discover that it was Sunday, It’s kind of like an alcohol blackout, So yes, getting the dosage just right — and never going above that dosage — is key with phenibut.

  31. Hmm, gonna have to try it. Major Depression, Refractory Type (treatment resistant).

    Best drug I ever tried was LSD. Used with care, it’s absolutely wonderful.

  32. Hey Will,

    Clarification about the taking with Caffeine regimen — do you mean “wait for 4 hours after taking Phenibut” to take the caffeine (as I saw how you mentioned it first.)? Or do you mean take the caffeine pill and Phenibut right together?

    Thank you for this article!

  33. I would like to share an interesting experience regarding Phenibut. I began to feel stuck in a rut due to the lack of motivation/lethargy. I researched nootropics and nutrition also began exercising (mainly cardio). I started on supplements, drastically reduced carb intake and stopped drinking(lost 30 pounds in two months). Started taking 250mg of phenibut every other day with caffeine in the morning. As of now my mood has brightened, I feel like a weight has been lifted of my shoulders. Women are flirting with me everywhere I go (maybe the weight loss)? I am back to my old self. I’m sharing this to ask your advice. After reading your insightful articles, I value your opinion. How do you think this was all possible, and can this continue without phenibut? The phenibut “feeling” has subsided, but the good life aspects are still there. Should I discontinue or lower/taper the phenibut? Do any other supplements exist to use that cycle well with phenibut? I just don’t want this to end.

  34. Hi Will, Love your site.

    My phenibut arrives tomorrow and I will probably start with a dose on Sunday and Wednesday, possibly working in the third day once I figure out the effects. I know you take it fasted in the morning, but eating breakfast for me is non-negotiable. Would you suggest taking on an emptier stomach maybe 2-3 hours after breakfast?

  35. Thanks buddy. Just took my first serving today and very curious about the impact. I’m starting with 1 gram serving and going from there. Thanks Will – will give you feedback asap.

  36. Hey Will – thanks for doing this write up. do you still take Phenibut three times a week? Have you noticed any long term negative effects? Just got my supply today and trying to figure out what best regimen is.

  37. Hi Will,
    I have a sales job where I work from 1pm to 9pm. I’ve been taking about 1g of Phenibut around 11am with lunch lately and I was wondering whether it would be better if I took it fasted in the am and then maybe redosed around 4 to keep the high going? I’m new to Phenibut so I’m just trying to get my regimen right for days when I decide to use it.

    Thanks for all your help,

  38. Nice article.
    As someone with prior drug and alcohol abuse issues who’s been sober now over 30 years I’d like to say I wouldn’t necessarily not recommend it but you have to be doing other things in your life to balance out what this helps provide. Meditation, movement, connection with others among them. I Have been on antidepressants for a little over a year and because of things like Phenibut, lemon balm and Ashwagandha I’ve been able to cut that amount in half with no deleterious effects on my mental state. In fact it’s improved.
    I would recommend this over Xanax or anything else that is prescribed as it is far less dangerous and more beneficial.
    Last, but not least I have only ever taken 200mg-325mg MAX in 1 day and have not taken it more than twice a week. It could be that since I don’t take other substances I’m more sensitive or something else, but I find that amount is just perfect for a great baseline of relaxation and the other things you described that lingers nicely into the next day.

  39. I’m needing to taper from 1mg Xanax three times daily prescribed by dr. I suffer from chronic anxiety, PTSD and bipolar II. Will this help with the withdrawals and what is your recommended dosage? I am a 50 year old female that has been prescribed Xanax most of my life. Being my dr is moving to another state and relocating isn’t an option I would like to try this if you have a regimen you suggest with fact backing up that it will lesson the withdrawal and won’t become dependent on phenibut.

  40. I’ve taken Phenibut quite a few times and studied the effects on me. I don’t believe Phenibut is that good when it comes to sleeping. I believe, a healthy sleep requires REM and dreaming, but every time I took Phenibut, I never dreamed. I was only able to sleep for about 4 hours, and I was completely oblivious to anything going on in the house… I was really out. I was still functional, though, if someone would wake me up. My dosage was 1/2 teaspoon at night. More than that would be unhealthy, imho. The best part of Phenibut, it gave me a positive and uplifting attitude on the day after my sleep.

    I believe, that when you take Phenibut during the day, it builds up in the body, and when your metabolism slows down at night, the Phenibut will kick in, so be careful not to take too much at night after taking a dosage during the day. I did that the first time I took it, and I was wiped out the following morning, and I couldn’t keep my balance. Essentially, I took a teaspoon (10 a.m.) and I didn’t feel anything, and because I didn’t feel anything after that, I took another teaspoon (3 p.m.). I still didn’t feel anything. That night, I took 1/2 teaspoon, and I really began to feel it. I don’t think Phenibut fully worked on me while I was active and alert during the daytime, but it caught up with me after I slowed down at night.

    I think some of the positives that are being written up about Phenibut are imaginary, so people really need to be truthful to themselves and not believe every good thing they read about it. Because the Phenibut didn’t allow me to dream at all (I normally dream a lot), I wonder if Phenibut might be bad for the brain. What if it causes Altzheimer’s Disease, for example?

  41. Obviously everyone is different. So what might be good for some, won’t be for others. I know people who have ruined their lives taking drugs, and I also know people who have enhanced their lives taking drugs. I know some one who was totally destroyed by weed. I know someone who put himself through the law school with meth. No two people are going to be a like in every way. So of course, be careful whatever you do.

    And always remember, the one thing in this world that can destroy you quicker than drugs is pussy. Be just as careful with whom you lay. How do you think most men become depressed? Pussy can be a lot more addictive than any drug and can even kill you. Not all pussy is good pussy. Some can even be offensive.

  42. Phenibut has actually helped my rage tremendously. I’m scared of not having it for that reason, I know I need psychological help but I’ve done therapy before with no help. Phenibut gives me the patience to not let things that would usually make me snap get to me. I feel in control. Is there something similar to Phenibut? I only use 1 gram on Wednesdays or Thursdays if I forget, I don’t feel like I need it physically, butbit definitely helps break up the week. I also started using kratom. Life’s been good.

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